Journal: Journal of the Pediatric Orthopaedic Society of North America

Article Title: Concentrated Bone Marrow Aspirate With Extracellular Matrix Grafting for Osteochondral Lesions of the Talus in Pediatric and Adolescent Patients

doi: 10.1016/j.jposna.2026.100324

Figure Lengend Snippet: Intraoperative arthroscopic images of the same child. Panel A demonstrates the lesion with softened overlying cartilage. Panel B is the lesion after lesion bed preparation with removal of unhealthy cartilage and curettage to a stable base of subchondral bone. Panel C is the ECM-BMAC graft sealed with fibrin glue. ECM-BMAC, extracellular matrix combined with bone marrow aspirate concentrate.

Article Snippet: A layer of Tisseel fibrin sealant (Baxter International, Deerfield, IL, USA) is then applied to seal the ECM-BMAC in place, which is allowed 5-10 min to cure.

Techniques:

Journal: International Forum of Allergy & Rhinology

Article Title: Burst Pressure and Fatigue Durability of Commercially Available Duraplasty Sealants

doi: 10.1002/alr.70132

Figure Lengend Snippet: (a) Burst pressures of six sealants were tested at cure times of 15 min, 2 h, and 24 h, in a 1 cm defect model. The dotted line shows the high normal intracranial pressure value (25 cm H 2 O) . Different letters indicate distinct Tukey groups within each sealant ( p < 0.05). A Box‐Cox transformation was applied to the VISTASEAL data due to non‐normal data distribution. Data shown as mean ± standard deviation. (b) The sealants were cured for 15 min, and then, to mimic current intraoperative usage, the sealants were tested when placed above the graft. The dotted line shows the normal intracranial pressure value (25 cm H 2 O) . *indicates statistical significance ( p < 0.05), whereas n.s. indicates no statistical significance ( p > 0.05). Data shown as mean ± standard deviation.

Article Snippet: Cook Biotech Incorporated (d/b/a Evergen) donated the Biodesign Duraplasty Graft, and Johnson & Johnson MedTech donated the VISTASEAL fibrin sealant used for all experiments.

Techniques: Transformation Assay, Standard Deviation

Journal: International Forum of Allergy & Rhinology

Article Title: Burst Pressure and Fatigue Durability of Commercially Available Duraplasty Sealants

doi: 10.1002/alr.70132

Figure Lengend Snippet: Aside from VISTASEAL and DuraSeal, the terminal burst pressures of all other sealants were unaffected by the cyclic fatigue. Figure 2 shows typical burst pressure versus time curves for (a) simple burst pressure test and (b) cyclic burst pressure test with five cycles of 15 s each. (c) A comparison of burst pressures obtained from single burst pressure tests with those obtained after cyclic burst pressure tests. Data for the normal burst pressure tests were re‐graphed from Figure . The dotted line shows the normal intracranial pressure value (25 cm H 2 O) . Due to non‐normal data distribution, a non‐parametric Wilcoxon test with α = 0.05 was used to test statistical significance. (d) Average cycles sustained by each sealant during the cyclic test. TISSEEL and TachoSil were able to withstand 3 and 4.6 cycles on average, respectively. Coseal and Adherus withstood 4.9 and 4.5 cycles, respectively. A non‐parametric Wilcoxon test with α = 0.05 was used to test statistical significance. The sealants were applied using the bottom application method and cured for 15 min. *Indicates statistical significance ( p < 0.05), whereas n.s. indicates no statistical significance ( p > 0.05). NA = Not Applicable, as the sealants were unable to withstand cyclic pressure testing.

Article Snippet: Cook Biotech Incorporated (d/b/a Evergen) donated the Biodesign Duraplasty Graft, and Johnson & Johnson MedTech donated the VISTASEAL fibrin sealant used for all experiments.

Techniques: Comparison